Ensayo clínico NCT04198766 · Non-Small Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer

Ensayo clínico NCT04198766 (fase I/II) figura como «en reclutamiento» en ClinicalTrials.gov.

Patología: Non-Small Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer · Intervenciones registradas: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatin AUC-6, Pemetrexed 500 mg/m2, Cisplatin 75mg/m2, Paclitaxel 200mg/m2, Nab paclitaxel 100mg/m2, Gemcitabine (1000 mg/m2) · Fechas registradas (fuente): 2019-12-10, 2033-07, 2019-12-13, 2026-11-06.

Resumen del estudio (fuente: ClinicalTrials.gov, texto original en inglés):

This is a Phase 1/2, open-label, non-randomized, 4-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of INBRX 106 administered as a single agent or in combination with the anti-PD-1 checkpoint inhibitor (CPI) pembrolizumab (Keytruda®). KEYTRUDA is a registered trademark of Merck Sharp \& Dohme LLC, a subsidiary of Merck \& Co., Inc., Rahway, NJ, USA.

Fuente: https://clinicaltrials.gov/study/NCT04198766