Pneumopathie liée aux inhibiteurs de checkpoints immunitaires : analyse rétrospective de l’incidence en vie réelle chez des patients atteints de cancer du poumon [étude IMPEREAL]

Obiettivo generale

To generate real-world epidemiological evidence on the incidence, clinical-radiological phenotypes, and risk factors of checkpoint inhibitor–related pneumonitis (CIP) in lung cancer patients, bridging the gap between trial data and practice. The study will provide insights on CIP incidence and multidimensional characteristics, potentially informing future research and refinement of diagnostic and…

Risultati attesi

Comprehensive characterization of real-world CIP epidemiology in a 10-year lung cancer cohort, including accurate incidence rates by ICI class, identified risk factors, multidimensional clinical phenotypes, and outcome patterns. Dissemination of findings through peer-reviewed publications and intern…