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2025 call Biomarcatori

Dr. Giovanna Polcaro

Ricercatrice UNISA Baronissi

📍 Università degli Studi di Salerno — Dipartimento di Medicina, Chirurgia ed Odontoiatria

Grant received: €3.000
Immuno-SAFE

Test salivare per la previsione delle reazioni avverse immuno-correlate (IRAEs) in NSCLC

Sviluppo di un test non invasivo basato su biomarcatori salivari (genetici, microbioma, immunologici) per predire chi tra i pazienti con tumore al polmone svilupperà reazioni avverse immuno-correlate (IRAEs) prima dell'inizio della terapia. Approccio precision medicine + medicina di laboratorio accessibile.

Scientific abstract

Immuno-SAFE: a first-in-class saliva-based genetic test for early prediction of immune-related adverse events in non–small cell lung cancer immunotherapy

Obiettivo generale

To advance precision oncology by implementing Immuno-SAFE, a rapid and non-invasive system predicting severe irAEs in NSCLC patients eligible for anti-PD-1/PD-L1 immunotherapy. The project aims to improve treatment personalization, enhance patient safety, reduce avoidable hospitalizations, and support the regional and national transition toward more efficient, sustainable immunotherapy management.

Risultati attesi

Early and accurate identification of NSCLC patients at high risk of severe irAEs, enabling more personalized and safer immunotherapy pathways. Reduction of treatment interruptions, emergency admissions, and irAE-related healthcare costs. Strengthened precision oncology services across regional cente…

Project key data

Formal title
Immuno-SAFE: a first-in-class saliva-based genetic test for early prediction of immune-related adverse events in non–small cell lung cancer immunotherapy
Expected duration
24 months
Funding
€3.000
Research centre
Dipartimento di Medicina, Chirurgia ed Odontoiatria; Baronissi (SA), 84081; Università degli studi di Salerno

Details

Call edition
Strongers for Research 2025
Awarded on
31 marzo 2026
Source
Bando 2025 — Comunicazione premio 31/03/2026

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